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KMID : 0361519940050010071
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Korean Journal of Psychopharmacology
1994 Volume.5 No. 1 p.71 ~ p.76
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An Open Tfial of Fluoxetine in the treatment of Premature Ejaculation
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이홍식
송동호/이호석/전지용/기선완/최형기/유계준
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Abstract
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In a 8-week open label clinical study. Eleven male patients with DSM-III-R premature ejaculation were treated with fluoxetine, a selective inhibitor of serotonin reuptake. After two weeks of washout period, each patient was assigned to receive
fluoxetine. Which was given once-daily 20mg for one wwek or more. And then was titrated to 60mg depending on either the clinical responses or the side effects. A within-subjects comparison of pre-and post-treatment self-visual analogue'scale
scores
for
sexual desire, anxiety for rapid djaculation. Spouse's satisfaction with ejaculation or overall sexual function revealed a significant improvemen. Also fluoxetine treatment produced significant improvements in Hamllton Rating Scale for Depression
scores
and SCL-90-R rating scale scores. These data suggest that serotonergic antidepressant may be effective in treating rapid ejaculation in male and underline the need to carry out a double-blind, placebo controlled trial to confirm these results.
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KEYWORD
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